Fluid Sterilization by Filtration

Hardcover
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Author: Peter R. Johnston

ISBN-10: 0849319773

ISBN-13: 9780849319778

Category: Mechanical Engineering - General & Miscellaneous

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Completely revised and updated, Fluid Sterilization by Filtration, Third Edition discusses the use of gas and fluid filtration systems in sterilization technology. Packed with information useful to both the novice and the expert, it includes line-drawing illustrations, filtration setups, and plots of math functions illustrating fluid flows through filter media built from a random packing of solids. The book provides in-depth discussions of general filtration, specific membranes used in filtration, integrity testing, earlier filtration steps, and cross-flow filtration. It also includes a useful, updated appendix of worldwide contacts and many sources for equipment, supplies, and information. Booknews For professionals in the pharmaceutical manufacturing industry, discusses the structure of the membranes and the integrity test relating to the final filtering of a liquid drug that is required by the US Food and Drug Administration just before it is packaged. The main concern is that the entire process must be sterile. The topics include the bubble-point test, measuring airflow in the diffusion zone, liquid and gas flow through the filter media, filter capacity in constant-flow and constant-pressure filtration, and cross-flow filtration. Revised from the 1992 edition based on comments from readers. Annotation c. by Book News, Inc., Portland, Or.

Ch. 1Liquid Flow through Filter MediaCh. 2Gas Flow through Filter MediaCh. 3The most Probable Pore-Size DistributionCh. 4Characterizing Filter Media Using Fluid Intrusion MeasurementsCh. 5Particles in FluidsCh. 6Describing Filtration EfficiencyCh. 7Structure and Permeability of Filter MediaCh. 8Different Views of FiltrationCh. 9Filtering LiquidsCh. 10Filtering GassesCh. 11The Rating of a Membrane Filter MediumCh. 12Cross-Flow FiltrationCh. 13Capacity of a Filter Medium in Constant-Pressure FiltrationCh. 14Capacity of a Filter Medium in Constant-Flow FiltrationCh. 15Capacity of a Filter Medium in Variable-Pressure and Variable-Flow FiltrationReferencesIndex